Due to depleted estrogen levels in the skin, peri- and postmenopausal women commonly experience a very specific set of skin conditions. These include increased dryness, decreased elasticity, and increased wrinkling. Few products and technologies have been specifically developed for this demographic and as our population ages, a higher proportion of a woman's life is spent postmenopause. The underlying deficiencies, elicited by reduced estrogen levels, are a lack of collagen synthesis and of cell proliferation and migration, and a reduced blood supply. This article reviews current and potential strategies for addressing these factors.