Treating patients with adult acne is a common challenge that dermatologists face.Adult acne differsfrom adolescent acne in its chronicity and typical clinical presentation.Successful therapeutic regimenstarget the multiple pathogenic factors that cause acne while considering the properties of adult skin.Acombination of topical and oral medications and adjunctive procedures should be tailored to the adultpatient’s need for optimal results.Recent advances in these areas have increased options for therapeu-tic armamentaria.Particular attention should be paid to formulations that are compatible with the drysensitive skin of many adults with acne.Proper skin care,an essential component of effective acne ther-apy that is necessary for patient compliance,should be emphasized.