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Case Report

Facial Photoaging Treated With Salicylic Acid–Enhanced Photodynamic Therapy
Casey AS, Ferris LK
Cosmet Dermatol. 2007;20:646-649.

Photoaging refers to skin damage that occurs from chronic exposure to UV radiation. These changes include roughness, sallowness, rhytides, pigmentary changes, erythema, telangiectasias, and sebaceous hyperplasia. Photodynamic therapy (PDT) offers a convenient and effective treatment option for photoaging. Because it acts as a photosensitizer, 5-aminolevulinic acid (5-ALA) is sometimes used as a treatment adjuvant in PDT, rendering the PDT more effective. We describe a new technique of using a 30% salicylic acid peel immediately prior to 5-ALA application in order to enhance penetration of 5-ALA. In our patient, this technique produced significant improvement in the skin, including decreased lentigines and more even skin texture, after just one treatment session. By combining these techniques, we propose that a more effective outcome can be produced with a single treatment session, thereby decreasing the number of treatments needed to produce the desired effect.


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