Short pulses of UV light in the 300- to 380-nm wavelength have been proven to effectively treat dermatoses, such as psoriasis and vitiligo. Lasers with handheld phototherapy modules that can direct UV light to more specific treatment areas may offer patients and clinicians a highly effective alternative treatment to full-body lightbox UV phototherapy as a standard therapy or to complement topical, injectable, or oral therapies for the treatment of psoriasis and vitiligo.